UFC 322 Expert Picks: Predictions for the Main Card

UFC 322 Expert Picks: Predictions for the Main Card

This article is part of our UFC Picks series.

The biggest card of the year takes place Saturday at Madison Square Garden, featuring No. 2 pound-for-pound fighter Islam Makhachev looking to move up to welterweight and claim a new belt against Jack Della Maddalena. In the co-main event, the female GOAT may be crowned, as Zhang Weili looks to take the flyweight strap from Valentina Shevchenko.

As a reminder, the following selections are purely picks. If you're looking for betting or fantasy-specific breakdowns of these fights, check out the following articles on RotoWire:

UFC 322 DraftKings Picks
UFC 322 Betting Picks
UFC 322 Fight Breakdowns
UFC 322 DFS Preview

We also have a MMA DFS Lineup Optimizer to try if you're looking to try out different combinations of fighters or generate multiple lineups, plus UFC 322 odds from every major sportsbook.

MMA Expert Picks & Predictions: UFC 322 Pay-Per-View Card

MATCHUP

WEIGHT 

CLASS

JONJAKECHRIS

(C) Jack Della Maddalena (+220) vs.

Islam Makhachev (-270)

Welterweight
Championship

MakhachevMakhachevMakhachev
(C) Valentina Shevchenko (-130) vs.
Zhang Weili (+110)

Women's
Flyweight
Championship

ZhangZhangZhang
Sean Brady (-142) vs.
Michael Morales (+120)

Welterweight

MoralesMoralesMorales
Leon Edwards (+164) vs.
Carlos Prates (-198)

Welterweight

PratesPratesPrates
Benoit Saint-Denis (-215) vs.
Beneil Dariush (+165)

Lightweight

Saint-DenisSaint-DenisDariush
     
UFC 322 RECORD 4-14-13-2
2025 RECORD 36-2134-2325-32
2025 PERCENTAGE .632.596.439
2024 RECORD 45-1941-2339-25
2024 PERCENTAGE .703.641.610
2023 RECORD 42-2544-2335-32
2023 PERCENTAGE .627.657.522
2022 RECORD 34-2740-2125-26
2022 PERCENTAGE .557.656.490
2021 RECORD 35-2842-2137-26
2021 PERCENTAGE .556.667.586
2020 RECORD 36-1834-2028-26
2020 PERCENTAGE .667.630.519
2019 RECORD 39-1935-2332-26
2019 PERCENTAGE .672.603.552
ALL-TIME  362-219367-214 290-237
ALL-TIME PERCENTAGE .623.632.550

 

MATCHUP

WEIGHT 
CLASS

JOE
"SUNTZU"

COLE     DRAKE

(C) Jack Della Maddalena (+220) vs.

Islam Makhachev (-270)

Welterweight
Championship

MakhachevDella MaddalenaMakhachev
(C) Valentina Shevchenko (-130) vs.
Zhang Weili (+110)

Women's
Flyweight
Championship

ZhangShevchenkoZhang
Sean Brady (-142) vs.
Michael Morales (+120)

Welterweight

BradyBradyMorales
Leon Edwards (+164) vs.
Carlos Prates (-198)

Welterweight

EdwardsPratesPrates
Benoit Saint-Denis (-215) vs.
Beneil Dariush (+165)

Lightweight

Saint-DenisDariushSaint-Denis
     
UFC 322 RECORD 2-33-24-1
2025 RECORD 31-2635-2238-19
2025 PERCENTAGE .544.614.667
2024 RECORD 40-2440-2443-21
2024 PERCENTAGE .625.625.672
2023 RECORD 41-2644-2336-31
2023 PERCENTAGE .612.657.537
2022 RECORD 38-2339-2239-22
2022 PERCENTAGE .623.639.639
2021 RECORD 38-2543-2117-14
2021 PERCENTAGE .603.672.548
2020 RECORD 36-18N/AN/A
2020 PERCENTAGE .667N/AN/A
2019 RECORD 34-24N/AN/A
2019 PERCENTAGE .586N/AN/A
ALL-TIME 295-185198-110173-107
ALL-TIME PERCENTAGE .615.643.618

In search of a new, legal sportsbook? Get in on the action with our best sportsbook promo codes, as well as these selections for the best sports betting sites and sports betting apps.

THE PICKERS

Jon Litterine: RotoWire lead MMA beat writer and scribe for our weekly DrafKings preview. Lead analyst on the RotoWire MMA Podcast. Follow him on Twitter at @JonLitterine.

Jake Letarski: RotoWire.com Operations Manager, plus MMA and NCAA Hoops Senior Editor. Host on the RotoWire MMA Podcast and guest on the RotoWire Fantasy Football Podcast. Follow him on Twitter at @RotoJake.

Chris Olson: Contributor at RotoWire to "Fight IQ, presented by RotoWire," as well as The MMA MashupDFS Baseballa MMA gambling columnist and fight recaps. Follow him on Twitter at @RealChrisOlson.

Joe "SunTszu": Known more commonly by his Twitter handle @SunTszu, Joe is a Hedge Fund Executive by day and high-volume DFS player by night. He is a 2x "Bracket Challenge" & "Gotham qualifier. You can also find him as one of the original contributors of "Fight IQ, presented by RotoWire," a DFS-centric video breakdown. He is also a co-creator of the "Creating Alpha in DFS" podcast.

Cole Shelton: Cole Shelton is a full-time sports writer focusing on MMA. His work has appeared on BJPenn.com, CBC Sports, Sports Betting Dime and Blue Jays Nation. He currently pens the MMA Best Bets column on RotoWire. Follow him on Twitter at @ColeShelton91.

Drake Burden: Drake is a proven DFS winner with multiple four-figure paydays under his belt. He took an interest to writing MMA during the pandemic and is active in various Discords and other social media communities. Follow him on Twitter at @DBurdz.

RotoWire has the latest in UFC betting odds & fighter prop bets for every event, plus compares markets across multiple legal sportsbooks.

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ABOUT THE AUTHOR
Jake Letarski
RotoWire Editor for College Basketball and MMA. Frequent podcaster, plus radio and video guest. Follow Jake on Twitter at @RotoJake.
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