RotoWire.com, home to a host of real money sports betting promos, once again asked ChatGPT to project this week's NFL games.
We asked the AI program to complete 10 simulations for each NFL Week 12 game, and it cranked out results with game scores for each simulation by using NFL rosters and injury updates as of Nov. 19. We also asked the program to provide a margin of victory for each simulated matchup. RotoWire found these results from AI for NFL Week 12 games:
ChatGPT Predicts NFL Week 12 Results
Matchup | Result | Visitors Avg. MOV | Home Avg.MOV |
BUF at HOU |
| 8.7 | NA |
NYJ at BAL |
| NA | 12.4 |
PIT at CHI |
| 5.3 | 4.0 |
NE at CIN |
| 9.6 | 2.0 |
NYG at DET |
| NA | 10.7 |
MIN at GB |
| 4.0 | 5.7 |
IND at KC |
| 2.7 | 7.7 |
SEA at TEN |
| 8.5 | 3.8 |
JAX at ARI |
| 6.8 | 3.0 |
CLE at LV | 5-5 | 3.2 | 6.8 |
PHI at DAL |
| 5.0 | 5.7 |
ATL at NO |
| 3.0 | 8.9 |
TB at LAR |
| 2.5 | 9.1 |
CAR at SF |
| 3.0 | 7.4 |
Bills 9-0-1
Ravens 9-0-1
Patriots 8-2
Lions 10-0
Packers 7-3
Chiefs 7-3
Seahawks 6-4
Jaguars 6-4
Eagles 7-3
Saints 8-2
Rams 8-2
49ers 9-1Teams on a bye: Denver Broncos, Los Angeles Chargers, Miami Dolphins, Washington Commanders
These projected results might differ from moneylines you'll see for Week 12 NFL odds offered at various sportsbooks.
Which Week 12 Games Are Too Close To Call?
The only game that was tied at 5-5 after 10 simulations was the (ahem) barnburner between the 2-8 Browns and the 2-8 Raiders in Las Vegas. Nobody wants to watch this mess, including Browns and Raiders fans.
So we'll pick the red-hot 
Chicago Bears as the team to focus on this week.
On the heels of six consecutive non-winning seasons, Chicago (7-3) has won seven of its past eight games after starting 0-2 and has soared to the top of the NFC North under first-year head coach Ben Johnson. The Bears have been a pleasant surprise for Windy City fans and NFL betting backers.
Bears quarterback Caleb Williams (above) is still undergoing some growing pains in his second season, but he's much more consistent than he was last season as a rookie. The No. 1 overall pick in the 2024 draft out of USC has seen his completion percentage dip a bit (from 62.5% in 2024 to 59.7% in 10 starts this season) but his yards per attempt has risen (from 6.3 YPA to 7.2) and he has led five fourth-quarter comebacks, tops in the NFL.
The 2023 Heisman Trophy winner has yet to have a 300-yard passing game in 2025, but he dents defenses with his legs (272 yards and three touchdowns rushing) and his mobility has allowed him to cut his sack numbers drastically. In 2024, Williams was sacked 68 times, the most in the NFL, for an average of 4.0 per game. This season he has been taken down 16 times, or 1.6 sacks on average.
At BetMGM Sportsbook, the Bears had +625 preseason odds to win their division. Now they're at +350, as of Nov. 19, in a tight race. The Lions (+135) and Packers (+140) are ahead of Chicago on the operator's board despite trailing the Bears in the NFC North standings.
The 
Pittsburgh Steelers come to Soldier Field this week, seeking a bit more consistency themselves.
QB Aaron Rodgers is the biggest question mark, as he fractured a bone in his left (non-throwing) wrist last week against the Bengals. Rodgers is questionable but several reports indicate that he'll play against the Bears, who are projected to win in six out of 10 simulations that we ran.
The Seahawks (over the Titans) and Jaguars (against the Cardinals) are also projected to win six out of 10 times in our simulated games.
Our reviews of the best sportsbook apps at RotoWire.com will keep you up to date all year round.
Week 12 NFL AI Projections Q&A
Q: How did ChatGPT simulate NFL Week 12 games?
A: RotoWire ran 10 simulations for every Week 12 matchup using ChatGPT, with rosters updated as of Nov. 19, 2025. Each game produced projected scores, a winner, and a calculated average margin of victory (MOV). This allowed us to compare not only who wins most often but also how decisively they win.
Q: Which teams dominated the ChatGPT simulations?
A: The San Francisco 49ers (9-1 over the Carolina Panthers), Detroit Lions (10-0 over the New York Giants), Buffalo Bills (9-0-1 against the Houston Texans) and Baltimore Ravens (9-0-1 facing the New York Jets) are predicted to show the most dominance over their opponents in Week 12, according to ChatGPT.
Q: What were the closest or most balanced matchups in the simulations?
A: For Week 12, ChatGPT only projected one matchup as dead even after 10 simulations. That was between the Cleveland Browns (average margin of victory 3.2 points) at the Las Vegas Raiders (AMOV 6.8), with a 5-5 tie.
