This article is part of our DraftKings NBA series.
Wednesday's expanded slate brings one of the deepest DFS boards of the week, with shifting NBA starting lineups, a packed NBA injury report and multiple high-usage stars in action. This DraftKings breakdown leans on updated NBA player projections, matchup data and usage trends to identify top targets, expected chalk and salary-saving value plays. With several contenders navigating injuries and rotation changes, staying current on NBA news, depth charts and lineup construction is critical for building competitive rosters. Whether you're optimizing builds, tracking fantasy basketball stats, or searching for reliable DFS value, this guide provides a clear path for attacking Wednesday's NBA DFS slate.
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NBA Games Today
CHI at DET: Bulls 7-10 on road; Pistons 13-3 at home
TOR at CHR: Raptors 10-7 on road; Hornets 7-10 at home
WAS at PHI: Wizards 4-13 on road; 76ers 9-9 at home
DEN at BOS: Nuggets 14-7 on road; Celtics on four-game winning streak, 11-5 at home
NOR at ATL: Pelicans on eight-game slide, 2-13 on road; Hawks 6-11 at home
ORL at BRO: Magic 8-11 on road; Nets 5-13 at home
LAC at NY: Clippers 4-13 on road; Knicks on four-game slide, 15-4 at home
PHO at MEM: Suns 9-10 on road; Grizzlies 8-9 at home
UTA at OKC: Jazz on four-game slide, 4-12 on road; Thunder 17-2 at home
LAL at SAN: Lakers on three-game winning streak, 13-5 on road; Spurs 12-5 at home
HOU at POR: Rockets 11-9 on road; Trail Blazers on three-game winning streak, 8-9 at home
MIL at GS: Bucks 7-11 on road; Warriors 11-5 at home
For the latest spreads and over/unders, visit RotoWire's NBA Odds page. There you can also find player props, futures, picks, articles and sportsbook bonus codes.
NBA Injuries Today
For all the latest updates, visit RotoWire's NBA Injury News page and our comprehensive NBA Injury Report.
CHI - Matas Buzelis (illness): Probable; Coby White (calf): Questionable; Jalen Smith (concussion), Zach Collins (toe), Josh Giddey (hamstring): OUT
DET - Duncan Robinson (calf), Caris LeVert (knee): Probable; Cade Cunningham (wrist): Questionable; Jalen Duren (ankle), Tobias Harris (hip): OUT
TOR - Jakob Poeltl (back): OUT
CHR - Moussa Diabate (wrist), Tidjane Salaun (ankle): Probable; Brandon Miller (knee): Questionable; Ryan Kalkbrenner (elbow): OUT
WAS - Khris Middleton (knee), CJ McCollum (quadriceps), Kyshawn George (hip): OUT
PHI - Joel Embiid (knee), Kelly Oubre (knee), Trendon Watford (adductor): Probable
DEN - Jamal Murray (ankle), Aaron Gordon (hamstring), Christian Braun (ankle), Tim Hardaway (illness), Jalen Pickett (lower leg), Spencer Jones (illness): Probable; Nikola Jokic (knee), Cameron Johnson (knee), Jonas Valanciunas (calf): OUT
BOS - Josh Minott (ankle): OUT
NOR - Trey Murphy (back), Herbert Jones (ankle): Questionable; Jose Alvarado (oblique), Saddiq Bey (hip): OUT
ATL - Onyeka Okongwu (illness): Questionable; Trae Young (quadriceps): OUT
ORL - Franz Wagner (ankle), Jalen Suggs (knee), Moritz Wagner (knee): OUT
BRO - Ben Saraf (knee): OUT
LAC - James Harden (shoulder): Probable; Bogdan Bogdanovic (hamstring): OUT
NY - Josh Hart (ankle), Landry Shamet (shoulder): OUT
PHO - Jalen Green (hamstring), Jamaree Bouyea (concussion): OUT
MEM - Jaren Jackson (illness): Probable; Ja Morant (calf), Santi Aldama (ankle), Vince Williams (knee): Questionable; Zach Edey (ankle), Cedric Coward (ankle): OUT
UTA - Ace Bailey (hip): Questionable; Kevin Love (rest): OUT
OKC - Shai Gilgeous-Alexander (knee): Questionable; Isaiah Hartenstein (calf), Alex Caruso (back), Jaylin Williams (heel): OUT
LAL - LeBron James (foot): Questionable; Austin Reaves (calf), Rui Hachimura (calf): OUT
SAN - Victor Wembanyama (knee): Questionable; Devin Vassell (adductor): OUT
HOU - Alperen Sengun (ankle): OUT
POR - Kris Murray (back), Jrue Holiday (calf), Jerami Grant (Achilles), Scoot Henderson (hamstring): OUT
MIL - Taurean Prince (neck): OUT
GS - Draymond Green (ankle): Probable; Gary Payton (ankle): Questionable; Seth Curry (back): OUT
Elite NBA DFS Picks
Guards
Jamal Murray, Nuggets 
($9,700) at Celtics
Murray is dealing with a sprained left ankle but is listed as probable to play Wednesday after sitting out Monday's win over the 76ers -- the second leg of a back-to-back set. The star point guard should continue to take on increased playmaking duties with Nikola Jokic (knee) sidelined, as Murray has averaged 10.0 assists per game over his last four appearances. He hasn't posted fewer than 42.8 DK points over that stretch, during which he has averaged 25.5 points and 6.3 rebounds in 38.0 minutes per tilt.
Devin Booker, Suns 
($8,500) at Grizzlies
Booker enters a promising matchup against a Memphis squad that is on the second night of a back-to-back set. The star guard has finished with 32.0-plus DK points in nine of his last 11 outings, during which he has averaged 27.2 points, 5.5 assists and 3.5 rebounds in 32.9 minutes per contest. In his last outing against Memphis on Oct. 29, Booker racked up 46.0 DK points in a losing effort.
Forwards/Centers
Kawhi Leonard, Clippers 
($10,100) at Knicks
Leonard has been on a tear of late, with the Clippers looking to work their way back into the playoff picture. The star forward has generated 38.8 or more DK points in nine straight games, averaging 33.6 points, 8.2 rebounds, 4.2 assists, 2.3 steals and 1.3 blocks in 37.2 minutes per contest over that stretch.
Michael Porter, Nets 
($8,700) vs. Magic
Porter continues to operate as Brooklyn's top offensive option and has scored 24-plus points in six straight games. The 27-year-old forward has finished with at least 40.8 DK points in each of those six outings, averaging 26.8 points, 8.7 rebounds, 3.8 assists and 1.0 steals across 34.2 minutes per contest over that span. The Magic are also on the second half of a back-to-back set and will remain without Franz Wagner (ankle) and Jalen Suggs (knee).
Joel Embiid, 76ers 
($9,200) vs. Wizards
Embiid has returned to form of late and will look to stay productive in a favorable matchup against a Washington squad that is on the second leg of a back-to-back. The star big man has logged 37.0 or more DK points in eight consecutive contests, during which he has averaged 29.1 points, 8.5 rebounds, 3.8 assists and 1.1 blocks in 33.9 minutes per tilt.
Expected NBA DFS Chalk
Jalen Johnson, Hawks 
($10,600) vs. Pelicans
The rising star has notched at least 40.3 DK points in 17 straight games, tallying 10 double-doubles and six triple-doubles during that span. With Trae Young (quadriceps) remaining sidelined, Johnson should continue to see increased playmaking duties. Over that 17-game stretch, he has averaged 25.9 points, 11.2 rebounds, 9.8 assists and 1.1 steals across 37.2 minutes per game.
Mid-Range NBA DFS Picks
VJ Edgecombe, 76ers ($6,700) vs. Wizards
Edgecombe has logged 40-plus minutes in four straight games and has recorded at least 43.5 DK points in each of them. The No. 3 overall pick in the 2025 NBA Draft has averaged 22.8 points, 5.3 rebounds, 4.8 assists, 3.0 steals and 1.5 blocks per game over that stretch, and he has a prime opportunity to remain productive against a lackluster Wizards defense Wednesday.
Derik Queen, Pelicans 
($6,300) at Hawks
Queen hasn't been aggressive as a scorer of late but could take more shots Wednesday if Trey Murphy (back) and Herbert Jones (ankle) are downgraded to out for the second leg of New Orleans' back-to-back set. Queen has contributed more than 32.2 DK points in eight of his last 10 outings, averaging 14.0 points, 9.3 rebounds, 4.5 assists, 1.3 blocks and 1.2 steals across 28.3 minutes per game during that stretch.
NBA DFS Value Picks
Moussa Diabate, Hornets 
($5,300) vs. Raptors
Diabate continues to be included on the injury report due to a right wrist sprain, though he's probable to suit up for a second consecutive contest. With the Hornets shorthanded at center, the 23-year-old should continue to take on an increased role. He has registered 31.5 or more DK points in five of his last six outings (five starts), averaging 8.3 points, 12.2 rebounds, 2.8 assists and 1.5 steals in 31.3 minutes per game during that span.
Jock Landale, Grizzlies 
($4,900) vs. Suns
The Australian big man has started back-to-back games and could see increased playing time if Jaren Jackson (illness) or Santi Aldama (ankle) are ruled out. Landale chipped in 32.0-plus DK points in each of those two games, during which he totaled 32 points, 19 rebounds, five assists and one block on 54.2 percent shooting from the field.
Ajay Mitchell, Thunder 
($4,800) vs. Jazz
Shai Gilgeous-Alexander was a late addition to the injury report due to right knee bursitis, which is never a good sign for a player's availability. Even if the reigning MVP is cleared to play, Mitchell has still been a consistent source of production off the bench. He has finished with at least 20.5 DK points in seven straight appearances, averaging 13.0 points, 3.4 rebounds, 3.3 assists and 1.7 steals in 23.4 minutes per tilt during that span.
